Does Vitamin D Deficiency Cause Autism?

In the past few weeks, there have been a couple of reports about Vitamin D in “Scientific American” magazine which both have bearings on autism.

Vitamin D Deficiency Affects the US

The first report was about how Vitamin D deficiency is soaring in the US, according to a study published in the “Archives of Internal Medicine”. The study claimed that a whopping three quarters of US teens and adults have a deficiency of vitamin D - that’s quite an incredible figure and makes you wonder why.

child in sunglassesThe study’s author, Adit Ginde, from the University of Colorado Denver School of Medicine, puts this vitamin D deficiency down to skin cancer prevention measures such as wearing long sleeves and using sunscreen ( sun protection of just factor 15 can cut the skin’s ability to manufacture vitamin D by 99%) and points out that there are actually very few dietary sources of vitamin D. Vitamin D is known as the “sunshine vitamin” because the skin produces vitamin D when it is exposed to the sun. By protecting ourselves from sun exposure, to reduce our risk of melanoma, we are cutting our levels of vitamin D.

Is There a Link between Lack of Sun and Autism?

But what has all this got to do with autism? Doesn’t a vitamin D deficiency lead to bone problems, such as rickets, osteoporosis and arthritis, not autism?

Well, yes, but experts are now wondering if a growth in vitamin D deficiencies has got something to do with the growth in autism. This theory is the result of two preliminary studies in Minnesota and Sweden, and the findings of these studies are discussed in the second article in “Scientific American” magazine.

Both Sweden and Minnesota have large Somali immigrant communities who seem to be overrepresented in the total number of children with autism in each area. In Minnesota, Somali families began arriving in 1993 and the number of children with autism in their community has jumped from 0 out of 1,773 in 1993, to 43 out of 2,029 in 2007. In Sweden, records of Somali children born in Stockholm between 1988 and 1998 have been studied and researchers concluded that Somali children in Stockholm were 3-4 times more likely to suffer with autism than non-Somali children in the city.

The Somali communities in both cities just can’t understand it. In Stockholm, the Somali people call autism “The Swedish Disease” because they had never seen it in Somalia, and Huda Fara, a Somali molecular biologist working in Minnesota, says “We never saw such a disease in Somalia. We do not even have a word for it.”

So why is autism hitting the Somali community so badly?

The only link that researchers could see was to do with sunlight. Both Minnesota and Stockholm are northern latitude countries and so have less hours of sunlight than equatorial Somalia. This means that the Somali communities were having less sun exposure in their new countries and therefore less vitamin D. Adit Ginde also points out that people with darker skins synthesize vitamin D more slowly. It has also been noted that Somali women (including pregnant women) were covering themselves completely when going outside in their new communities, much more than they would have done back in Somali where their whole community was Muslim. Their dress obviously affected their sun exposure levels.

Some experts are arguing that the increase of rates of autism in the Somali communities is just because autism was not being diagnosed in Somalia, due to a lack of awareness, but others are arguing that there may be a vitamin D link with autism. Proponents of this theory put forward the findings of a 2007 review, by Tulane University’s Allan Kalueff, on 20 different studies on animals and humans. Kalueff concluded that vitamin D was essential in gestation and early infanthood for “normal brain functioning”.

Further Evidence

Another study that backs up the vitamin D theory is research carried out by Cornell University and published in “Archives of Pediatrics and Adolescent Medicine” in November last year. This study found that children who lived in counties in Washington, Oregon and California, where there were more overcast days and more rain, were twice as likely to have autism than children living in drier counties in the same state. Michael Waldman, co-author of the study, said “Our research is sufficiently suggestive of an environmental trigger for autism associated with precipitation, of which vitamin D deficiency is one possibility. Further research focused on vitamin D deficiency is clearly warranted.”

Research into vitamin D and autism is ongoing, including a pilot study by Gene Stubbs (associate professor emeritus of psychiatry and pediatrics at Oregon Health & Science University) with pregnant women. Stubbs is giving 5,000 IUs of vitamin D3 to pregnant women who already have at least one child with autism. He is then going to give the women 7,000 IUs while they are breastfeeding. It will be interesting to see the results of this study.

What Can You Do?

If you are pregnant, you may want to consider taking a special pregnancy supplement which contains vitamin D and making sure that you eat plenty of vitamin D rich foods, such as milk, fatty fish and eggs. However, the best source of vitamin D is the sun, so try and get a little sun each day. Experts agree that 10-15 minutes of sunlight a day, at breakfast time or in the evening when the sun’s rays are not so damaging, can boost vitamin D levels without harming the skin.

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6 Responses to “Does Vitamin D Deficiency Cause Autism?”

  1. Tiffany Says:

    Ok this is a awesome article, I have noticed my son does “better” in the summer..good read!! Thanks for the kind comments on my page!!

  2. Steve Madojemu Says:

    Did research on Somalians kids with autism look at the likely effects on vacinations on these people who didn’t use to vacinate before moving to the US? If sunshine is the only thing missing, this is environmental, what about new food and medications taken in their new environment. Any reserach into autism must take ALL factors into consideration - NUTRITION, ENVIRONMENT, GENETICS AS WELL AS EVERY EXPOSURE TO HEAVY METALS & HISTORY OF ALL INTAKES (PARTICULARLY VACINATIONS).

  3. admin Says:

    Thanks for your comment, Tiffany.

    Steve, you’re right that these Somali children would be facing other changes too - vaccinations, exposure to pollution and heavy metal etc. and I’m not sure how the preliminary study ruled out these factors. There are some interesting articles on vitamin D and autism at http://www.vitamindcouncil.org/health/autism/, linking the rise in autism with the rise in vitalin D deficiency. I think that vitamin D is another factor that we have to consider and research.

  4. New Autism Cure - breakthrough treatments and cures for autism » Blog Archive » Does Vitamin D Deficiency Cause Autism? - Part 2 Says:

    [...] « Does Vitamin D Deficiency Cause Autism? [...]

  5. Bowman Says:

    I have an autistic spectrum disorder, and I recently found out that I had low vitamin D. I started supplementation and the positive effects were profound and immediate. A blood test a month after I started supplementation showed that vitamin D levels were going up.

    Then I hit a wall and started to feel terrible again. There are studies that show vitamin D increasing the levels of lead in the blood (see references below). One possible explanation for this is that vitamin D stimulates the production of glutathione, which some refer to as the body’s master antioxidant. Glutathione is also a natural chelator of heavy metals.

    So taking vitamin D could theoretically stimulate an endogenous chelation process, but as with many chelation therapies, symptoms can get much worse before they get better, because the metals that are stored in tissues are released into the bloodstream on their way out of the body.

    I have read through Dr Cannell’s theory on vitamin D. It’s important to note that Cannell is a psychiatrist, not a traditional MD. But his theory makes sense. There is other compelling theories on autism as well, including those related to heavy metals such as mercury and lead, and other research showing abnormal zinc and copper levels in autistic children. Not all studies have found a relationship between these metals and autism, but taking vitamin D’s natural chelation abilities into consideration could go some way towards tying these disparate theories together.

    As for myself, I continue to take vitamin D in the hope that I will get through a rough patch that is theoretically being caused by increased serum levels of lead and other metals that were in my system.

    Search for these studies to read about the relationship between lead and vitamin D:

    Elevated Blood Lead Concentrations and Vitamin D Deficiency in Winter and Summer in Young Urban Children

    Effects of vitamin D on the absorption and retention of lead

    Effect of Lead Ingestion on Functions of Vitamin D and its Metabolites

  6. admin Says:

    Interesting and I love your information on this connection between vitamin D and its chelating effect. Please be careful on taking Vitamin D as it is afterall a fat soluble vitamin which means we stored them on our body, and plus, we do get them from the sun as well especially in the summer or hot countries. Normally, this is how we take Vit D following a blood test called Vit D-25 to see where we stand. If we want to increase by say 50% we can dose about 6000 IU/day for 3 months or if we want to increase by 100% or twice your blood value, we can dose 10000 IU/day for 3 months. Please always follow up by the blood test. However, I see you are talking about using Vit D as therapeutic effect, i.e., chelating agent. This is quite possible but do consider other alternative first and be careful.

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